Three major antigens of Langerhans’ islets of pancreatic β-cells are glutamic acid decarboxylase (GAD), insulinoma-associated protein 2 (IA-2) and insulin. The determination of circulating autoantibodies against these structures are used for specific classification in diabetes mellitus  type I and LADA, as well as for diabetes prediction in first grade relatives of diabetic mellitus type I patients. Prevalence of Anti-IA2 in DM type I patients is 50-85%.

Name IRMA Anti-IA2
Ref. IM3652/IM3653
Method IRMA
Type Homogenous phase
Tests 50/100
Max. Activity (kBq) 50/2x50
Sensitivity 0.16 U/mL
Incubation conditions 16-20 hrs/2-8°C+1 hr/2-8°C
Calibrator range 0;0.75-50 U/mL
Sample volume (μL) 20
Sample form serum
Analyte info                      
Instructions for Use